Perturbing Endothelial Biomechanics via Connexin 43 Structural Disruption

Md. Mydul Islam; Robert L. Steward, Jr.

doi:10.3791/60034

Journal

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Biochemistry

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Biomecánica endotelial perturbando a través de Connexin 43 Interrupción Estructural

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Biochemistry

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JoVE Journal Biochemistry

Perturbing Endothelial Biomechanics via Connexin 43 Structural Disruption

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Biomecánica endotelial perturbando a través de Connexin 43 Interrupción Estructural

5,381 Views

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09:20 min

•

October 04, 2019

DOI:

10.3791/60034-v

DOI:

10.3791/60034-v

•

09:20 min

October 04, 2019

•

1 Views

Md. Mydul Islam¹, Robert L. Steward, Jr.^1,2

¹Department of Mechanical and Aerospace Engineering,University of Central Florida, ²Burnett School of Biomedical Sciences, College of Medicine,University of Central Florida

Summary

Aquí, presentamos un protocolo basado en la mecánica para interrumpir la conexión de separación de la conexión 43 y medir el impacto posterior que esto tiene en la biomecánica endotelial a través de la observación de tracciones y tensiones intercelulares.

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Biomecánica endotelial perturbando a través de Connexin 43 Interrupción Estructural

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Summary

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