Perturbing Endothelial Biomechanics via Connexin 43 Structural Disruption

Md. Mydul Islam; Robert L. Steward, Jr.

doi:10.3791/60034

Journal

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Biochemistry

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Perturbing Biomécanique endothéliale via Connexin 43 Structural Disruption

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Biochemistry

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JoVE Journal Biochemistry

Perturbing Endothelial Biomechanics via Connexin 43 Structural Disruption

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Perturbing Biomécanique endothéliale via Connexin 43 Structural Disruption

5,381 Views

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09:20 min

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October 04, 2019

DOI:

10.3791/60034-v

DOI:

10.3791/60034-v

•

09:20 min

October 04, 2019

•

1 Views

Md. Mydul Islam¹, Robert L. Steward, Jr.^1,2

¹Department of Mechanical and Aerospace Engineering,University of Central Florida, ²Burnett School of Biomedical Sciences, College of Medicine,University of Central Florida

Summary

Ici, nous présentons un protocole mécanique pour perturber la connexine de jonction d'écart 43 et mesurer l'impact ultérieur ceci a sur la biomécanique endothéliale par l'observation des tractions et des contraintes intercellulaires.

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Perturbing Biomécanique endothéliale via Connexin 43 Structural Disruption

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