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Perturbing endotheliale biomechanica via Connexin 43 structurele verstoring
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Biochemistry
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JoVE Journal Biochemistry
Perturbing Endothelial Biomechanics via Connexin 43 Structural Disruption
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Perturbing endotheliale biomechanica via Connexin 43 structurele verstoring

Nederlands

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5,381 Views

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09:20 min

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October 04, 2019

DOI:

10.3791/60034-v

DOI:
10.3791/60034-v

•

09:20 min
October 04, 2019

•

1 Views
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1Department of Mechanical and Aerospace Engineering,University of Central Florida, 2Burnett School of Biomedical Sciences, College of Medicine,University of Central Florida

Summary

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Hier presenteren we een op mechanica gebaseerd protocol om de gap junction connexin 43 te verstoren en de daaropvolgende impact te meten die dit heeft op endotheliale biomechanica via observatie van tracties en intercellulaire spanningen.

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Islam, M. M., Steward, Jr., R. L. Perturbing Endothelial Biomechanics via Connexin 43 Structural Disruption. J. Vis. Exp. (152), e60034, doi:10.3791/60034 (2019).

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