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Störende Endothelial Biomechanik über Connexin 43 Strukturelle Störung
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Biochemistry
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JoVE Journal Biochemistry
Perturbing Endothelial Biomechanics via Connexin 43 Structural Disruption
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Störende Endothelial Biomechanik über Connexin 43 Strukturelle Störung

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5,381 Views

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09:20 min

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October 04, 2019

DOI:

10.3791/60034-v

DOI:
10.3791/60034-v

•

09:20 min
October 04, 2019

•

1 Views
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1Department of Mechanical and Aerospace Engineering,University of Central Florida, 2Burnett School of Biomedical Sciences, College of Medicine,University of Central Florida

Summary

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Hier stellen wir ein mechanikbasiertes Protokoll vor, um den Spaltknoten-Anschluss 43 zu stören und die daraus resultierenden Auswirkungen auf die endotheliale Biomechanik durch Beobachtung von Traktionen und interzellulären Spannungen zu messen.

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Islam, M. M., Steward, Jr., R. L. Perturbing Endothelial Biomechanics via Connexin 43 Structural Disruption. J. Vis. Exp. (152), e60034, doi:10.3791/60034 (2019).

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