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Implantation und Überwachung eines orthotopischen Modells des menschlichen Pleuralmesothelioms bei athymischen Mäusen durch PET/CT
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JoVE 신문 면역학 및 감염병학
Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
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Implantation und Überwachung eines orthotopischen Modells des menschlichen Pleuralmesothelioms bei athymischen Mäusen durch PET/CT

6,603 Views

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07:54 min

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December 21, 2019

DOI:

10.3791/60272-v

DOI:
10.3791/60272-v

•

07:54 min
December 21, 2019

•

1 Views
, , , ,
1MicroPET/SPECT/CT Imaging Laboratory, Centre for BioMedical Imaging (CIBM), Division of Nuclear Medicine and Molecular Imaging,University Hospitals and University of Geneva, 2Division of Thoracic and Endocrine Surgery,University Hospitals and University of Geneva

Summary

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Dieser Artikel beschreibt die Erzeugung eines orthotopischen Mausmodells des menschlichen Pleuramesothelioms durch Implantation von H2052/484 Mesotheliomzellen in die Pleurahöhle immungeschwächter athymischer Mäuse. Die Längsüberwachung der Entwicklung intrapleuraler Tumoren wurde durch nicht-invasive multimodale [18F]-2-Fluor-2-Deoxy-D-Glucose-Positronen-Emissionstomographie und Computertomographie untersucht.

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Colin, D. J., Bejuy, O., Germain, S., Triponez, F., Serre-Beinier, V. Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice. J. Vis. Exp. (154), e60272, doi:10.3791/60272 (2019).

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