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Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
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JoVE Journal 免疫学と感染
Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

DOI:
10.3791/60272-v

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07:54 min

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December 21, 2019

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, , , ,
1MicroPET/SPECT/CT Imaging Laboratory, Centre for BioMedical Imaging (CIBM), Division of Nuclear Medicine and Molecular Imaging,University Hospitals and University of Geneva, 2Division of Thoracic and Endocrine Surgery,University Hospitals and University of Geneva

章

  • 00:05標題
  • 00:45Tumor Cell Implantation
  • 02:43[18F]FDG-PET/CT Imaging
  • 04:12Analysis of [18F]FDG-PET/CT Scans
  • 06:08Results: Malignant Pleural Mesothelioma Monitoring with [18F]FDG-PET/CT Imaging
  • 06:59Conclusion

概要

自動翻訳

自動翻訳

This article describes the generation of an orthotopic mouse model of human pleural mesothelioma by implantation of H2052/484 mesothelioma cells into the pleural cavity of immunocompromised athymic mice. The longitudinal monitoring of the development of intrapleural tumors was assessed by non-invasive multimodal [18F]-2-fluoro-2-deoxy-D-glucose positron emission tomography and computed tomography imaging.

タグ

Orthotopic ModelPleural MesotheliomaAthymic MicePET/CTImplantationMonitoringAnesthesiaBuprenorphinePovidone-iodineCell SuspensionHamilton SyringeAbsorbable SuturesFDGDose CalculatorRadioactivity

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