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Implantación y monitorización por PET/CT de un modelo ortotópico de mesotelioma pleural humano en ratones atímicos
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JoVE 신문 면역학 및 감염병학
Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
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Implantación y monitorización por PET/CT de un modelo ortotópico de mesotelioma pleural humano en ratones atímicos

6,603 Views

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07:54 min

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December 21, 2019

DOI:

10.3791/60272-v

DOI:
10.3791/60272-v

•

07:54 min
December 21, 2019

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1 Views
, , , ,
1MicroPET/SPECT/CT Imaging Laboratory, Centre for BioMedical Imaging (CIBM), Division of Nuclear Medicine and Molecular Imaging,University Hospitals and University of Geneva, 2Division of Thoracic and Endocrine Surgery,University Hospitals and University of Geneva

Summary

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Este artículo describe la generación de un modelo de ratón ortotópico de mesotelioma pleural humano mediante la implantación de células de mesotelioma H2052/484 en la cavidad pleural de ratones atímicos inmunocomprometidos. El monitoreo longitudinal del desarrollo de tumores intrapleurales se evaluó mediante tomografía multimodal no invasiva [18F]-2-fluoro-2-deoxy-D-glucose positron emission tomography and computed tomography.

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Cite this Article

Colin, D. J., Bejuy, O., Germain, S., Triponez, F., Serre-Beinier, V. Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice. J. Vis. Exp. (154), e60272, doi:10.3791/60272 (2019).

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