/

/

利用微流体装置进行机械刺激和高分辨率成像的研究C.线虫

JoVE 신문
신경과학

JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.

JoVE 신문 신경과학

Using a Microfluidics Device for Mechanical Stimulation and High Resolution Imaging of C. elegans

Please note that all translations are automatically generated. Click here for the English version.

利用微流体装置进行机械刺激和高分辨率成像的研究C.线虫

9,594 Views

•

10:39 min

•

February 19, 2018

DOI:

10.3791/56530-v

DOI:

10.3791/56530-v

•

10:39 min

February 19, 2018

•

3 Views

Holger Fehlauer*¹, Adam L. Nekimken*^1,2, Anna A. Kim^1,2, Beth L. Pruitt^1,2,3, Miriam B. Goodman^1,2, Michael Krieg⁴

¹Department of Molecular and Cellular Physiology,Stanford University, ²Department of Mechanical Engineering,Stanford University, ³Department of Bioengineering,Stanford University, ⁴Group of Neurophotonics and Mechanical Systems Biology,The Institute of Photonic Sciences (ICFO)

Summary

美国匹茨堡研究的新工具需要了解机械应力是如何激活生化通路并引起生物学反应的。在这里, 我们展示了一种新的方法, 选择性机械刺激固定化动物与微流控器陷阱, 允许高分辨率成像的细胞反应。

Explore More Videos

Microfluidics Mechanical Stimulation High-resolution Imaging C. Elegans Mechanobiology Sensory Biology Pressure Actuators GCaMP RFP Fluorescence Microscopy M9 Buffer Peristaltic Pump PDMS

Read Article