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Geração de Organoides de Vasos Sanguíneos Humanos a partir de Células-Tronco Pluripotentes
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Generation of Human Blood Vessel Organoids from Pluripotent Stem Cells

Geração de Organoides de Vasos Sanguíneos Humanos a partir de Células-Tronco Pluripotentes

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4,532 Views

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09:46 min

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January 20, 2023

DOI:

10.3791/64715-v

DOI:
10.3791/64715-v

•

09:46 min
January 20, 2023

•

54 Views
,
1School of Biomedical Engineering,University of British Columbia, 2Life Sciences Institute,University of British Columbia, 3Department of Medical Genetics,University of British Columbia, 4Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA)

Summary

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Este protocolo descreve a geração de vasos sanguíneos auto-organizadores a partir de células-tronco pluripotentes e pluripotentes induzidas humanas. Essas redes vasculares exibem uma extensa e conectada rede endotelial circundada por pericitos, actina de músculo liso e membrana basal contínua.

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Cite this Article

Werschler, N., Penninger, J. Generation of Human Blood Vessel Organoids from Pluripotent Stem Cells. J. Vis. Exp. (191), e64715, doi:10.3791/64715 (2023).

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