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Heterotope zervikale Herztransplantation der Maus mit Gefäßmanschetten
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Immunology and Infection
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JoVE Journal Immunology and Infection
Mouse Heterotopic Cervical Cardiac Transplantation Utilizing Vascular Cuffs
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Heterotope zervikale Herztransplantation der Maus mit Gefäßmanschetten

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2,599 Views

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08:44 min

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June 23, 2022

DOI:

10.3791/64089-v

DOI:
10.3791/64089-v

•

08:44 min
June 23, 2022

•

9 Views
, , , , ,
1Department of Surgery,Washington University School of Medicine, 2Department of Surgery,The University of Maryland, 3Department of Pathology & Immunology,Washington University School of Medicine, 4Department of Medicine,Washington University School of Medicine

Summary

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Maus-Herztransplantationsmodelle stellen wertvolle Forschungswerkzeuge für die Untersuchung der Transplantationsimmunologie dar. Das vorliegende Protokoll beschreibt die heterotope zervikale Herztransplantation der Maus, bei der Manschetten auf die gemeinsame Halsschlagader des Empfängers und den Lungenarterienstamm des Spenders gelegt werden, um einen laminaren Blutfluss zu ermöglichen.

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Cite this Article

Li, W., Shepherd, H. M., Krupnick, A. S., Gelman, A. E., Lavine, K. J., Kreisel, D. Mouse Heterotopic Cervical Cardiac Transplantation Utilizing Vascular Cuffs. J. Vis. Exp. (184), e64089, doi:10.3791/64089 (2022).

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