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Mouse Heterotopic Cervical Cardiac Transplantation Utilizing Vascular Cuffs
JoVE Journal
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JoVE Journal İmmünoloji ve Enfeksiyon
Mouse Heterotopic Cervical Cardiac Transplantation Utilizing Vascular Cuffs

Mouse Heterotopic Cervical Cardiac Transplantation Utilizing Vascular Cuffs

2,599 Views

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08:44 min

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June 23, 2022

DOI:

10.3791/64089-v

DOI:
10.3791/64089-v

•

08:44 min
June 23, 2022

•

9 Views
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1Cerrahi Bölümü,Washington Üniversitesi Tıp Fakültesi, 2Cerrahi Bölümü,The University of Maryland, 3Department of Pathology & Immunology,Washington Üniversitesi Tıp Fakültesi, 4Tıp Fakültesi,Washington Üniversitesi Tıp Fakültesi

Özet

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Mouse cardiac transplantation models represent valuable research tools for studying transplantation immunology. The present protocol details mouse heterotopic cervical cardiac transplantation that involves the placement of cuffs on the recipient's common carotid artery and the donor's pulmonary artery trunk to allow for laminar blood flow.

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Cite this Article

Li, W., Shepherd, H. M., Krupnick, A. S., Gelman, A. E., Lavine, K. J., Kreisel, D. Mouse Heterotopic Cervical Cardiac Transplantation Utilizing Vascular Cuffs. J. Vis. Exp. (184), e64089, doi:10.3791/64089 (2022).

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