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Mouse Heterotopic Cervical Cardiac Transplantation Utilizing Vascular Cuffs
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JoVE Journal 免疫学と感染
Mouse Heterotopic Cervical Cardiac Transplantation Utilizing Vascular Cuffs

Mouse Heterotopic Cervical Cardiac Transplantation Utilizing Vascular Cuffs

2,599 Views

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08:44 min

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June 23, 2022

DOI:

10.3791/64089-v

DOI:
10.3791/64089-v

•

08:44 min
June 23, 2022

•

9 Views
, , , , ,
1外科,Washington University 医学部, 2外科,The University of Maryland, 3Department of Pathology & Immunology,Washington University 医学部, 4医学部,Washington University 医学部

概要

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Mouse cardiac transplantation models represent valuable research tools for studying transplantation immunology. The present protocol details mouse heterotopic cervical cardiac transplantation that involves the placement of cuffs on the recipient's common carotid artery and the donor's pulmonary artery trunk to allow for laminar blood flow.

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Cite this Article

Li, W., Shepherd, H. M., Krupnick, A. S., Gelman, A. E., Lavine, K. J., Kreisel, D. Mouse Heterotopic Cervical Cardiac Transplantation Utilizing Vascular Cuffs. J. Vis. Exp. (184), e64089, doi:10.3791/64089 (2022).

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