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Realización de Xenoinjertos musculares esqueléticos humanos en ratones inmunodeficientes
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Developmental Biology
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JoVE Journal Developmental Biology
Performing Human Skeletal Muscle Xenografts in Immunodeficient Mice
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Realización de Xenoinjertos musculares esqueléticos humanos en ratones inmunodeficientes

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9,478 Views

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07:48 min

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September 16, 2019

DOI:

10.3791/59966-v

DOI:
10.3791/59966-v

•

07:48 min
September 16, 2019

•

10 Views
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1Graduate Program in Cellular and Molecular Medicine,Johns Hopkins University School of Medicine, 2Department of Neurology,Johns Hopkins University School of Medicine, 3Kennedy Krieger Institute, 4Department of Neuroscience,Johns Hopkins University School of Medicine

Summary

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Las enfermedades humanas complejas pueden ser difíciles de modelar en los sistemas de modelos de laboratorio tradicionales. Aquí, describimos un enfoque quirúrgico para modelar la enfermedad muscular humana a través del trasplante de biopsias musculares esqueléticas humanas en ratones inmunodeficientes.

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Cite this Article

Britson, K. A., Black, A. D., Wagner, K. R., Lloyd, T. E. Performing Human Skeletal Muscle Xenografts in Immunodeficient Mice. J. Vis. Exp. (151), e59966, doi:10.3791/59966 (2019).

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