Journal
/
Developmental Biology
/
Esecuzione di Xenografi muscolari scheletrici umani in topi immunodeficienti
JoVE Journal
Developmental Biology
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Developmental Biology
Performing Human Skeletal Muscle Xenografts in Immunodeficient Mice
Please note that all translations are automatically generated. Click here for the English version.

Esecuzione di Xenografi muscolari scheletrici umani in topi immunodeficienti

italiano

Automatically Generated

9,465 Views

•

07:48 min

•

September 16, 2019

DOI:

10.3791/59966-v

DOI:
10.3791/59966-v

•

07:48 min
September 16, 2019

•

10 Views
, , ,
1Graduate Program in Cellular and Molecular Medicine,Johns Hopkins University School of Medicine, 2Department of Neurology,Johns Hopkins University School of Medicine, 3Kennedy Krieger Institute, 4Department of Neuroscience,Johns Hopkins University School of Medicine

Summary

Automatically generated

Le malattie umane complesse possono essere difficili da modellare nei sistemi di modelli di laboratorio tradizionali. Qui, descriviamo un approccio chirurgico per modellare la malattia muscolare umana attraverso il trapianto di biopsie muscolari scheletriche umane in topi immunodeficienti.

Explore More Videos

Human Skeletal Muscle XenograftsImmunodeficient MiceMuscle Disease ModelingPreclinical Therapeutic TestingHuman Muscle Cell BiologyRare Or Acquired Muscle DiseasesMuscle BiopsyNOD-Rag-gamma MouseTibialis AnteriorExtensor Digitorum LongusPeroneus LongusSurgical Procedure

Read Article

Cite this Article

Britson, K. A., Black, A. D., Wagner, K. R., Lloyd, T. E. Performing Human Skeletal Muscle Xenografts in Immunodeficient Mice. J. Vis. Exp. (151), e59966, doi:10.3791/59966 (2019).

Download .ris file

Copy

Share Video

.

Copy