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Cefoperazon behandelten Maus-Modell der klinisch relevanten<em> Clostridium difficile</em> Dehnungs R20291
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Immunology and Infection
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JoVE Journal Immunology and Infection
Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
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Cefoperazon behandelten Maus-Modell der klinisch relevanten<em> Clostridium difficile</em> Dehnungs R20291

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12,056 Views

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06:51 min

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December 10, 2016

DOI:

10.3791/54850-v

DOI:
10.3791/54850-v

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06:51 min
December 10, 2016

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5 Views
, , ,
1Department of Population Health and Pathobiology,North Carolina State University College of Veterinary Medicine, 2Department of Pathology and Laboratory Medicine, Lineberger Comprehensive Cancer Center,University of North Carolina School of Medicine

Summary

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Dieses Protokoll beschreibt die Cefoperazon Maus - Modell von Clostridium difficile - Infektion (CDI) eine klinisch relevante und genetisch-lenkbar - Stamm verwenden, R20291. Schwerpunkt auf der klinischen Krankheitsüberwachung, C. difficile Bakterien-Enumeration, Toxin Zytotoxizität und histopathologischen Veränderungen im gesamten CDI in einem Mausmodell werden im Protokoll aufgeführt.

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Cite this Article

Winston, J. A., Thanissery, R., Montgomery, S. A., Theriot, C. M. Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291. J. Vis. Exp. (118), e54850, doi:10.3791/54850 (2016).

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