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Céfopérazone traité Souris Modèle de Cliniquement pertinentes<em> Clostridium difficile</em> Strain R20291
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Immunology and Infection
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JoVE Journal Immunology and Infection
Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
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Céfopérazone traité Souris Modèle de Cliniquement pertinentes<em> Clostridium difficile</em> Strain R20291

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12,056 Views

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06:51 min

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December 10, 2016

DOI:

10.3791/54850-v

DOI:
10.3791/54850-v

•

06:51 min
December 10, 2016

•

5 Views
, , ,
1Department of Population Health and Pathobiology,North Carolina State University College of Veterinary Medicine, 2Department of Pathology and Laboratory Medicine, Lineberger Comprehensive Cancer Center,University of North Carolina School of Medicine

Summary

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Ce protocole décrit le modèle de souris céfopérazone d'infection à Clostridium difficile (CDI) en utilisant une souche cliniquement pertinente et génétiquement traitable, R20291. L' accent mis sur la surveillance clinique de la maladie, C. énumération bactérienne difficile, la toxine cytotoxicité, et des changements histopathologiques tout au long de CDI dans un modèle de souris sont détaillés dans le protocole.

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Cite this Article

Winston, J. A., Thanissery, R., Montgomery, S. A., Theriot, C. M. Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291. J. Vis. Exp. (118), e54850, doi:10.3791/54850 (2016).

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