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Use of Frozen Tissue in the Comet Assay for the Evaluation of DNA Damage
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Use of Frozen Tissue in the Comet Assay for the Evaluation of DNA Damage

Use of Frozen Tissue in the Comet Assay for the Evaluation of DNA Damage

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11:30 min

March 24, 2020

DOI:

11:30 min
March 24, 2020

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Summary

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This protocol describes several procedures for preparing high quality frozen tissue samples at the time of necropsy for use in the comet assay to assess DNA damage: 1) minced tissue, 2) scraped epithelial cells from the gastrointestinal tract, and 3) cubed tissue samples, requiring homogenization using a tissue mincing device.

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