Journal
/
유전학
/
Bronchoalveolar Lavage Exosomes Lipopolysaccharide-geïnduceerde septische long letsel
JoVE 신문
유전학
JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다.  전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
JoVE 신문 유전학
Bronchoalveolar Lavage Exosomes in Lipopolysaccharide-induced Septic Lung Injury
Please note that all translations are automatically generated. Click here for the English version.

Bronchoalveolar Lavage Exosomes Lipopolysaccharide-geïnduceerde septische long letsel

10,697 Views

•

08:27 min

•

May 21, 2018

DOI:

10.3791/57737-v

DOI:
10.3791/57737-v

•

08:27 min
May 21, 2018

•

2 Views
, ,
1Department of Veterans Affairs,Atlanta VAMC, 2Division of Pulmonary and Critical Care Medicine, Department of Medicine,Emory University

Summary

Automatically generated

Muizen blootgesteld aan intraperitoneaal LPS afscheiden exosomes in Broncho-alveolaire lavage (BAL) vloeistof die zijn ingepakt met miRNAs. Met behulp van een systeem co cultuur tonen we dat exosomes vrijgegeven in de BAL vloeistof expressie van strakke junction eiwitten in bronchiale epitheliale cellen verstoren en verhogen van expressie van pro-ontsteking cytokinen die long letsel accentueren.

Explore More Videos

Bronchoalveolar LavageExosomesLipopolysaccharideSeptic Lung InjuryAcute Lung InjuryAcute Respiratory Distress SyndromeAlveolar MicroenvironmentExosome IsolationCentrifugationUltracentrifugationSyringe FiltrationExosome Characterization

Read Article

Cite this Article

Yuan, Z., Bedi, B., Sadikot, R. T. Bronchoalveolar Lavage Exosomes in Lipopolysaccharide-induced Septic Lung Injury. J. Vis. Exp. (135), e57737, doi:10.3791/57737 (2018).

Download .ris file

Copy

Share Video

.

Copy