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肺発生生物学と疾患をモデル化するための人工多能性幹細胞からの3D全肺オルガノイドの生成
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Developmental Biology
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JoVE Journal Developmental Biology
Generation of 3D Whole Lung Organoids from Induced Pluripotent Stem Cells for Modeling Lung Developmental Biology and Disease
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肺発生生物学と疾患をモデル化するための人工多能性幹細胞からの3D全肺オルガノイドの生成

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7,172 Views

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09:45 min

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April 12, 2021

DOI:

10.3791/62456-v

DOI:
10.3791/62456-v

•

09:45 min
April 12, 2021

•

18 Views
, , ,
1Department of Pediatrics,University of California, San Diego School of Medicine, 2Sanford Consortium for Regenerative Medicine, 3Sanford Burnham Prebys Medical Discovery Institute

Summary

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本稿では、近位および遠位上皮肺細胞と共に近位および遠位上皮肺細胞の両方を含む3次元全肺オルガノイドに対する誘導多能性幹細胞のステップ指向分化について説明する。

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Cite this Article

Leibel, S. L., McVicar, R. N., Winquist, A. M., Snyder, E. Y. Generation of 3D Whole Lung Organoids from Induced Pluripotent Stem Cells for Modeling Lung Developmental Biology and Disease. J. Vis. Exp. (170), e62456, doi:10.3791/62456 (2021).

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