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Generazione di organoidi polmonari interi 3D da cellule staminali pluripotenti indotte per la modellazione della biologia e della malattia dello sviluppo polmonare
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Developmental Biology
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JoVE Journal Developmental Biology
Generation of 3D Whole Lung Organoids from Induced Pluripotent Stem Cells for Modeling Lung Developmental Biology and Disease
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Generazione di organoidi polmonari interi 3D da cellule staminali pluripotenti indotte per la modellazione della biologia e della malattia dello sviluppo polmonare

italiano

Automatically Generated

7,213 Views

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09:45 min

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April 12, 2021

DOI:

10.3791/62456-v

DOI:
10.3791/62456-v

•

09:45 min
April 12, 2021

•

18 Views
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1Department of Pediatrics,University of California, San Diego School of Medicine, 2Sanford Consortium for Regenerative Medicine, 3Sanford Burnham Prebys Medical Discovery Institute

Summary

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L'articolo descrive la differenziazione diretta graduale delle cellule staminali pluripotenti indotte in organoidi polmonari interi tridimensionali contenenti cellule polmonari epiteliali sia prossimali che distali insieme a mesenchima.

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Cite this Article

Leibel, S. L., McVicar, R. N., Winquist, A. M., Snyder, E. Y. Generation of 3D Whole Lung Organoids from Induced Pluripotent Stem Cells for Modeling Lung Developmental Biology and Disease. J. Vis. Exp. (170), e62456, doi:10.3791/62456 (2021).

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