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Un modelo in vitro para estudiar la agregación de Tau utilizando la transducción de neuronas humanas mediada por lentivirales
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Neuroscience
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JoVE Journal Neuroscience
An In Vitro Model for Studying Tau Aggregation Using Lentiviral-mediated Transduction of Human Neurons
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Un modelo in vitro para estudiar la agregación de Tau utilizando la transducción de neuronas humanas mediada por lentivirales

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05:51 min

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May 23, 2019

DOI:

10.3791/59433-v

DOI:
10.3791/59433-v

•

05:51 min
May 23, 2019

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3 Views
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1Department of Neurosciences,University of California, San Diego

Tags

Tau AggregationIn Vitro ModelHuman NeuronsLentiviral TransductionCell CultureDrug ScreeningDisease MechanismBasement Membrane MatrixNeural Stem Cell MediaBFGFDMEM-F12Penicillin-streptomycinCell ThawingCentrifugationCell SeedingConfluencyLentivirus Transduction

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Aulston, B., Liu, Q., Reilly, P., Yuan, S. H. An In Vitro Model for Studying Tau Aggregation Using Lentiviral-mediated Transduction of Human Neurons. J. Vis. Exp. (147), e59433, doi:10.3791/59433 (2019).

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