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An In Vitro Model for Studying Tau Aggregation Using Lentiviral-mediated Transduction of Human Neurons
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An In Vitro Model for Studying Tau Aggregation Using Lentiviral-mediated Transduction of Human Neurons
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May 23, 2019
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This protocol details a procedure in which human neuronal cultures are transduced with lentiviral constructs coding for mutant human tau. Transduced cultures display tau aggregates and associated pathologies.
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Aulston, B., Liu, Q., Reilly, P., Yuan, S. H. An In Vitro Model for Studying Tau Aggregation Using Lentiviral-mediated Transduction of Human Neurons. J. Vis. Exp. (147), e59433, doi:10.3791/59433 (2019).
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