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Design af cecal ligation og punktering og intranasal infektion Dual model af sepsis-induceret immunsuppression
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
DOI:

07:30 min

June 15, 2019

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Chapters

  • 00:00Title
  • 00:12Cecal Ligation and Puncture (CLP)
  • 03:29Secondary Intranasal Infection with Staphylococcus aureus
  • 05:52Results
  • 06:59Conclusion

Summary

Automatic Translation

Denne protokol beskriver teknikker til at måle infektiøse resultater underliggende sekundære hospitalserhvervede infektioner i immunsuppressiv tilstand, først ved at etablere cecal ligation/punktering mus derefter udfordre dem med intranasal infektion til at skabe en klinisk relevant model for immun undertrykkelses sepsis.

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