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Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
JoVE Revista
Inmunología y contagio
Author Produced
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JoVE Revista Inmunología y contagio
Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

DOI:

07:30 min

June 15, 2019

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Capítulos

  • 00:00Título
  • 00:12Cecal Ligation and Puncture (CLP)
  • 03:29Secondary Intranasal Infection with Staphylococcus aureus
  • 05:52Resultados
  • 06:59Conclusion

Summary

Traducción Automática

This protocol describes techniques to measure infectious outcomes underlying secondary hospital-acquired infections in the immunosuppressive condition, first by establishing cecal ligation/puncture mice then challenging them with intranasal infection to create a clinically relevant model of immunosuppression sepsis.

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