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Analyse von Iophenoxic Acid Analoga in Small Indian Mongoose (Herpestes Auropunctatus) Sera zur Verwendung als orale Tollwut-Impfung Biologischer Marker
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Immunology and Infection
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JoVE Journal Immunology and Infection
Analysis of Iophenoxic Acid Analogues in Small Indian Mongoose (Herpestes Auropunctatus) Sera for Use as an Oral Rabies Vaccination Biological Marker
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Analyse von Iophenoxic Acid Analoga in Small Indian Mongoose (Herpestes Auropunctatus) Sera zur Verwendung als orale Tollwut-Impfung Biologischer Marker

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5,751 Views

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11:28 min

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May 31, 2019

DOI:

10.3791/59373-v

DOI:
10.3791/59373-v

•

11:28 min
May 31, 2019

•

1 Views
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1US Department of Agriculture, Animal and Plant Health Inspection Service, Wildlife Services,National Wildlife Research Center, 2IDT Biologika GmbH,Am Pharmapark

Summary

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Wir boten in Gefangenschaft Mongooses Placebo orale Tollwut-ImpfstoffKöder mit Ethyl- oder Methyl-Iophenoxsäure als Biomarker und verifizierte Köderaufnahme mit einer neuartigen Flüssigchromatographie mit Tandem-Massenspektrometrie (LC-MS/MS) Methode an.

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Iophenoxic AcidMongoose SerumBiological MarkerOral Rabies VaccinationProtein PrecipitationMethyl-IPAEthyl-IPAAnalytical MethodHPLCQuantificationParts Per Billion

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Cite this Article

Berentsen, A. R., Sugihara, R. T., Payne, C. G., Leinbach, I., Volker, S. F., Vos, A., Ortmann, S., Gilbert, A. T. Analysis of Iophenoxic Acid Analogues in Small Indian Mongoose (Herpestes Auropunctatus) Sera for Use as an Oral Rabies Vaccination Biological Marker. J. Vis. Exp. (147), e59373, doi:10.3791/59373 (2019).

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