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Analysis of Iophenoxic Acid Analogues in Small Indian Mongoose (Herpestes Auropunctatus) Sera for Use as an Oral Rabies Vaccination Biological Marker
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JoVE Journal 免疫学と感染
Analysis of Iophenoxic Acid Analogues in Small Indian Mongoose (Herpestes Auropunctatus) Sera for Use as an Oral Rabies Vaccination Biological Marker

Analysis of Iophenoxic Acid Analogues in Small Indian Mongoose (Herpestes Auropunctatus) Sera for Use as an Oral Rabies Vaccination Biological Marker

DOI:
10.3791/59373-v

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11:28 min

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May 31, 2019

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, , , , , , ,
1US Department of Agriculture, Animal and Plant Health Inspection Service, Wildlife Services,National Wildlife Research Center, 2IDT Biologika GmbH,Am Pharmapark

章

  • 00:04標題
  • 00:30Preparation of Solutions and Standards
  • 04:13Sample Preparation
  • 08:19LC-MS/MS Analysis
  • 09:04Results: Iophenoxic Acid Results in Mongoose Serum
  • 10:44Conclusion

概要

自動翻訳

自動翻訳

We offered captive mongooses placebo oral rabies vaccine baits with ethyl or methyl iophenoxic acid as a biomarker and verified bait uptake using a novel liquid chromatography with tandem mass spectrometry (LC-MS/MS) method.

タグ

Iophenoxic AcidMongoose SerumBiological MarkerOral Rabies VaccinationProtein PrecipitationMethyl-IPAEthyl-IPAAnalytical MethodHPLCQuantificationParts Per Billion

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