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Aislamiento de los capilares cerebrales del cerebro humano fresco tejido
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Neuroscience
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JoVE Journal Neuroscience
Isolation of Cerebral Capillaries from Fresh Human Brain Tissue
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Aislamiento de los capilares cerebrales del cerebro humano fresco tejido

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12,293 Views

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06:35 min

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September 12, 2018

DOI:

10.3791/57346-v

DOI:
10.3791/57346-v

•

06:35 min
September 12, 2018

•

3 Views
, , , , , , , ,
1Sanders-Brown Center on Aging, Department of Pharmacology and Nutritional Sciences,University of Kentucky, 2Department of Pharmaceutical Sciences, College of Pharmacy,University of Kentucky, 3Department of Neuroscience,University of Kentucky

Summary

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Tubos capilares del cerebro aislado de tejido de cerebro humano pueden utilizarse como un modelo preclínico para estudiar la función de barrera bajo condiciones fisiológicas y fisiopatológicas. Aquí, presentamos un protocolo optimizado para aislar los capilares del cerebro del tejido de cerebro humano fresco.

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Cite this Article

Hartz, A. M., Schulz, J. A., Sokola, B. S., Edelmann, S. E., Shen, A. N., Rempe, R. G., Zhong, Y., Seblani, N. E., Bauer, B. Isolation of Cerebral Capillaries from Fresh Human Brain Tissue. J. Vis. Exp. (139), e57346, doi:10.3791/57346 (2018).

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