ジャーナル
/
神経科学
/
Isolation of Cerebral Capillaries from Fresh Human Brain Tissue
JoVE Journal
神経科学
このコンテンツを視聴するには、JoVE 購読が必要です。  サインイン又は無料トライアルを申し込む。
JoVE Journal 神経科学
Isolation of Cerebral Capillaries from Fresh Human Brain Tissue

Isolation of Cerebral Capillaries from Fresh Human Brain Tissue

12,332 Views

•

06:35 min

•

September 12, 2018

DOI:

10.3791/57346-v

DOI:
10.3791/57346-v

•

06:35 min
September 12, 2018

•

3 Views
, , , , , , , ,
1Sanders-Brown Center on Aging, Department of Pharmacology and Nutritional Sciences,University of Kentucky, 2Department of Pharmaceutical Sciences, College of Pharmacy,University of Kentucky, 3神経科学科,University of Kentucky

概要

Automatically generated

Isolated brain capillaries from human brain tissue can be used as a preclinical model to study barrier function under physiological and pathophysiological conditions. Here, we present an optimized protocol to isolate brain capillaries from fresh human brain tissue.

Explore More Videos

Cerebral CapillariesBlood-brain BarrierIsolationHomogenizationFicoll Density GradientFiltrationCentrifugation

Read Article

Cite this Article

Hartz, A. M., Schulz, J. A., Sokola, B. S., Edelmann, S. E., Shen, A. N., Rempe, R. G., Zhong, Y., Seblani, N. E., Bauer, B. Isolation of Cerebral Capillaries from Fresh Human Brain Tissue. J. Vis. Exp. (139), e57346, doi:10.3791/57346 (2018).

Download .ris file

Copy

Share Video

.

Copy