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Isolamento dei capillari cerebrali da tessuto cerebrale umano fresco
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Neuroscience
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JoVE Journal Neuroscience
Isolation of Cerebral Capillaries from Fresh Human Brain Tissue
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Isolamento dei capillari cerebrali da tessuto cerebrale umano fresco

italiano

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12,293 Views

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06:35 min

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September 12, 2018

DOI:

10.3791/57346-v

DOI:
10.3791/57346-v

•

06:35 min
September 12, 2018

•

3 Views
, , , , , , , ,
1Sanders-Brown Center on Aging, Department of Pharmacology and Nutritional Sciences,University of Kentucky, 2Department of Pharmaceutical Sciences, College of Pharmacy,University of Kentucky, 3Department of Neuroscience,University of Kentucky

Summary

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Capillari cerebrali isolate da tessuto cerebrale umano possono essere utilizzati come un modello preclinico per studiare la funzione di barriera in condizioni fisiologiche e fisiopatologiche. Qui, presentiamo un protocollo ottimizzato per isolare i capillari cerebrali da tessuto cerebrale umano fresco.

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Cite this Article

Hartz, A. M., Schulz, J. A., Sokola, B. S., Edelmann, S. E., Shen, A. N., Rempe, R. G., Zhong, Y., Seblani, N. E., Bauer, B. Isolation of Cerebral Capillaries from Fresh Human Brain Tissue. J. Vis. Exp. (139), e57346, doi:10.3791/57346 (2018).

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