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Singel-molekyl Manipulation av G-quadruplexes av magnetisk pincett
JoVE Journal
Biochemistry
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JoVE Journal Biochemistry
Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
DOI:

08:28 min

September 19, 2017

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Chapters

  • 00:05Title
  • 01:10Magnetic Tweezers Setup and Identification of Single dsDNA Tether
  • 04:43Single-molecule Manipulation of G4 on the Presence and Absence of Binding Proteins
  • 05:57Results: Single-molecule Manipulation of a G4 and Force-jump Measurements of G4 Unfolding
  • 07:46Conclusion

Summary

Automatic Translation

En enda-molekyl magnetisk pincett plattform att manipulera G-quadruplexes rapporteras, vilket möjliggör studier av G4 stabilitet och reglering av olika proteiner.

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