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Methyl-bindende DNA-Capture-Sequenzierung für Patientengewebe
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Genetics
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JoVE Journal Genetics
Methyl-binding DNA capture Sequencing for Patient Tissues
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Methyl-bindende DNA-Capture-Sequenzierung für Patientengewebe

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8,424 Views

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08:40 min

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October 31, 2016

DOI:

10.3791/54131-v

DOI:
10.3791/54131-v

•

08:40 min
October 31, 2016

•

14 Views
, , , , , , ,
1Department of Molecular Medicine,University of Texas Health Science Center at San Antonio, 2Greehey Children’s Cancer Research Institute,University of Texas Health Science Center at San Antonio

Summary

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Hier präsentieren wir ein Protokoll zu untersuchen, genomweite DNA-Methylierung in großem Maßstab klinischen Patienten-Screening-Studien unter Verwendung des Methyl-Bindung DNA Capture-Sequenzierung (MBDCap-seq oder MBD-seq) Technologie und die anschließende bioinformatische Analyse-Pipeline.

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Cite this Article

Jadhav, R. R., Wang, Y. V., Hsu, Y., Liu, J., Garcia, D., Lai, Z., Huang, T. H. M., Jin, V. X. Methyl-binding DNA capture Sequencing for Patient Tissues. J. Vis. Exp. (116), e54131, doi:10.3791/54131 (2016).

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