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Developmental Biology
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JoVE Journal Developmental Biology
Basement Membrane Matrix Encapsulated Cell Aggregation for Investigating Murine Spleen Tissue Formation
 

Basement Membrane Matrix Encapsulated Cell Aggregation for Investigating Murine Spleen Tissue Formation

Article DOI: 10.3791/66682-v • 07:30 min • June 28th, 2024
June 28th, 2024 •
1, 1, 1, 1, 1, 1
1Clem Jones Centre for Regenerative Medicine, Faculty of Health Sciences and Medicine, Bond University

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This article describes a protocol for aggregating and encapsulating spleen cells within a semi-solid basement membrane matrix. Basement membrane matrix constructs can be used in three-dimensional culture for studying organoid development, or for in vivo transplantation and tissue regeneration studies.

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Developmental Biology Spleen Biomedical Engineering Regenerative Medicine Cellular Biology Animal model Organoid
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