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Constructie van cyclische celdoordringende peptiden voor verbeterde penetratie van biologische barrières
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Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers
DOI:

10:12 min

September 19, 2022

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Chapters

  • 00:04Introduction
  • 01:10Equipment Preparation
  • 01:44Synthesis of FITC‐Labeled Linear R8 Peptide and FITC‐Labeled Stapled R8 Peptide
  • 05:49Exploration of the Cell‐to‐Cell Penetration of the Peptides Using Transwell Models
  • 07:06Results: Synthesis of FITC‐R8 and FITC‐sR8‐4 Using Solid‐Phase Peptide Synthesis and Evaluation of Their Trans‐Barrier Permeability
  • 09:06Conclusion

Summary

자동 번역

Dit protocol beschrijft de synthese van cyclische celdoordringende peptiden met aromatische dwarsverbanden en de evaluatie van hun permeabiliteit over biologische barrières heen.

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