This protocol describes the synthesis of cyclic cell-penetrating peptides with aromatic cross-links and the evaluation of their permeability across biological barriers.
Fang, D., Wang, R., Yu, X., Tian, Y. Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers. J. Vis. Exp. (187), e64293, doi:10.3791/64293 (2022).