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Optogenetic Manipulation of Neuronal Activity to Modulate Behavior in Freely Moving Mice
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행동분석학
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Optogenetic Manipulation of Neuronal Activity to Modulate Behavior in Freely Moving Mice

Optogenetic Manipulation of Neuronal Activity to Modulate Behavior in Freely Moving Mice

16,467 Views

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14:40 min

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October 27, 2020

DOI:

10.3791/61023-v

DOI:
10.3791/61023-v

•

14:40 min
October 27, 2020

•

57 Views
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1Biology and Chemistry, Synthetic Biology,University of Bremen, 2Advanced Fluorescence Microscopy, Faculty of Biology and Biotechnology,Ruhr-Universität Bochum

Summary

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With optogenetic manipulation of specific neuronal populations or brain regions, behavior can be modified with high temporal and spatial resolution in freely moving animals. By using different optogenetic tools in combination with chronically implanted optical fibers, a variety of neuronal modulations and behavioral testing can be performed.

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OptogeneticsNeuronal Activity행동분석학Freely Moving MiceOptical ImplantNeuronal ModulationCell Type-specificNeuronal CircuitryStereotactic SurgeryAnesthesiaImplantation

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Cite this Article

Berg, L., Gerdey, J., Masseck, O. A. Optogenetic Manipulation of Neuronal Activity to Modulate Behavior in Freely Moving Mice. J. Vis. Exp. (164), e61023, doi:10.3791/61023 (2020).

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