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Behavior
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JoVE Journal Behavior
Optogenetic Manipulation of Neuronal Activity to Modulate Behavior in Freely Moving Mice
 

Optogenetic Manipulation of Neuronal Activity to Modulate Behavior in Freely Moving Mice

Article DOI: 10.3791/61023-v • 14:40 min • October 27th, 2020
October 27th, 2020 •
1,2, 1,2, 1,2
1Biology and Chemistry, Synthetic Biology, University of Bremen, 2Advanced Fluorescence Microscopy, Faculty of Biology and Biotechnology, Ruhr-Universität Bochum

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Summary
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With optogenetic manipulation of specific neuronal populations or brain regions, behavior can be modified with high temporal and spatial resolution in freely moving animals. By using different optogenetic tools in combination with chronically implanted optical fibers, a variety of neuronal modulations and behavioral testing can be performed.

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Optogenetic Manipulation Neuronal Activity Behavior Modulation Freely Moving Mice Optogenetic Tools Optical Fibers Neuronal Modulations Behavioral Testing Neuronal Circuitries Precise Control Cell Types Microcircuits Preparation Optical Implant Ceramic Ferrule Glass Fiber Stripping Tool Superglue
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