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Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling
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October 11, 2018
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We describe a sleep deprivation technique known as gentle handling where investigators gently prod mice any time sleep behavior is observed. This method is a powerful tool that allows researchers to study the effects that chronic sleep restriction throughout development can have on future brain physiology and behavior.
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Lemons, A., Saré, R. M., Beebe Smith, C. Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling. J. Vis. Exp. (140), e58150, doi:10.3791/58150 (2018).
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