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Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling
JoVE Journal
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JoVE Journal Davranış
Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling

Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling

DOI:
10.3791/58150-v

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03:46 min

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October 11, 2018

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, ,
1Section on Neuroadaptation and Protein Metabolism, National Institute of Mental Health,'National Institutes of Health'

'Bölümler'

  • 00:04'Başlık'
  • 00:32Experimental Setup
  • 01:22Sleep Deprivation
  • 02:37Results: Chronic Sleep Restriction Alters Social Behavior
  • 03:12Conclusion

Özet

'Otomatik Çeviri'

'Otomatik Çeviri'

We describe a sleep deprivation technique known as gentle handling where investigators gently prod mice any time sleep behavior is observed. This method is a powerful tool that allows researchers to study the effects that chronic sleep restriction throughout development can have on future brain physiology and behavior.

'Etiketler'

Chronic Sleep DeprivationMouse PupsGentle HandlingPostnatal DevelopmentSleep RestrictionSleep Deprivation ProtocolControl GroupSleep MonitoringSociability TestSocial NoveltyRecovery Period

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