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Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling
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Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling

Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling

9,772 Views

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03:46 min

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October 11, 2018

DOI:

10.3791/58150-v

DOI:
10.3791/58150-v

•

03:46 min
October 11, 2018

•

7 Views
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1Section on Neuroadaptation and Protein Metabolism, National Institute of Mental Health,National Institutes of Health

Summary

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We describe a sleep deprivation technique known as gentle handling where investigators gently prod mice any time sleep behavior is observed. This method is a powerful tool that allows researchers to study the effects that chronic sleep restriction throughout development can have on future brain physiology and behavior.

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Cite this Article

Lemons, A., Saré, R. M., Beebe Smith, C. Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling. J. Vis. Exp. (140), e58150, doi:10.3791/58150 (2018).

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