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Een<em> In Vitro</em> Caseum Binding Assay die de penetratie van drugs in tuberculose-lesingen voorspelt
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An In Vitro Caseum Binding Assay that Predicts Drug Penetration in Tuberculosis Lesions
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Een<em> In Vitro</em> Caseum Binding Assay die de penetratie van drugs in tuberculose-lesingen voorspelt

11,457 Views

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12:17 min

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May 08, 2017

DOI:

10.3791/55559-v

DOI:
10.3791/55559-v

•

12:17 min
May 08, 2017

•

5 Views
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1Public Health Research Institute Centre, New Jersey Medical School,Rutgers, 2Tuberculosis Research Section, Laboratory of Clinical Infectious Diseases, NIAID,NIH

Summary

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Hier beschrijven we een werkwijze snel evenwicht dialyse (RED) drug binding aan ca- seum longtuberculose laesies en holtes meten. Het protocol wordt ook gebruikt met een schuimige-macrofaag afgeleide matrix met een effectieve surrogaat voor ca- seum.

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Sarathy, J. P., Liang, H. H., Weiner, D., Gonzales, J., Via, L. E., Dartois, V. An In Vitro Caseum Binding Assay that Predicts Drug Penetration in Tuberculosis Lesions. J. Vis. Exp. (123), e55559, doi:10.3791/55559 (2017).

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