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Drug Treatment and In Vivo Imaging of Osteoblast-Osteoclast Interactions in a Medaka Fish Osteoporosis Model
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Drug Treatment and In Vivo Imaging of Osteoblast-Osteoclast Interactions in a Medaka Fish Osteoporosis Model

Drug Treatment and In Vivo Imaging of Osteoblast-Osteoclast Interactions in a Medaka Fish Osteoporosis Model

9,055 Views

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08:53 min

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January 01, 2017

DOI:

10.3791/55025-v

DOI:
10.3791/55025-v

•

08:53 min
January 01, 2017

•

4 Views
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1Department of Biological Sciences,National University of Singapore, 2NUS Centre for Bioimaging Sciences (CBIS),National University of Singapore

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Small laboratory fish have become popular models for bone research on the mechanisms underlying human bone disorders and for the screening of bone-modulating drugs. In this report, we describe a protocol to assess the effect of alendronate on bone cells in medaka larvae with osteoporotic lesions.

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Cite this Article

Yu, T., Winkler, C. Drug Treatment and In Vivo Imaging of Osteoblast-Osteoclast Interactions in a Medaka Fish Osteoporosis Model. J. Vis. Exp. (119), e55025, doi:10.3791/55025 (2017).

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