Drug Treatment and <em>In Vivo</em> Imaging of Osteoblast-Osteoclast Interactions in a Medaka Fish Osteoporosis Model

Tingsheng Yu; Christoph Winkler

doi:10.3791/55025

ジャーナル

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発生生物学

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Drug Treatment and In Vivo Imaging of Osteoblast-Osteoclast Interactions in a Medaka Fish Osteoporosis Model

JoVE Journal
発生生物学

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JoVE Journal 発生生物学

Drug Treatment and In Vivo Imaging of Osteoblast-Osteoclast Interactions in a Medaka Fish Osteoporosis Model

Drug Treatment and In Vivo Imaging of Osteoblast-Osteoclast Interactions in a Medaka Fish Osteoporosis Model

9,055 Views

•

08:53 min

•

January 01, 2017

DOI:

10.3791/55025-v

DOI:

10.3791/55025-v

•

08:53 min

January 01, 2017

•

4 Views

Tingsheng Yu^1,2, Christoph Winkler^1,2

¹Department of Biological Sciences,National University of Singapore, ²NUS Centre for Bioimaging Sciences (CBIS),National University of Singapore

概要

Small laboratory fish have become popular models for bone research on the mechanisms underlying human bone disorders and for the screening of bone-modulating drugs. In this report, we describe a protocol to assess the effect of alendronate on bone cells in medaka larvae with osteoporotic lesions.

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Drug Treatment and In Vivo Imaging of Osteoblast-Osteoclast Interactions in a Medaka Fish Osteoporosis Model

概要

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