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CNSへの標的化物質送達のためのマウス顕微注入法<i>経由で</i>内頸動脈
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Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery
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CNSへの標的化物質送達のためのマウス顕微注入法<i>経由で</i>内頸動脈

10,622 Views

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06:41 min

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January 31, 2017

DOI:

10.3791/54804-v

DOI:
10.3791/54804-v

•

06:41 min
January 31, 2017

•

8 Views
, , ,
1Department of Biochemistry and Molecular Biology, Miller School of Medicine,University of Miami, 2The Jerzy Kukuczka Academy of Physical Education

Summary

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The present protocol describes a mouse microsurgery infusion technique, which effectively delivers substances directly into the brain via the internal carotid artery.

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Mouse MicrosurgeryInfusion TechniqueTargeted Substance DeliveryCNSInternal Carotid Artery신경과학Drug DeliveryPathogenExosomeMinimal TraumaNeuronal NetworkBrain ConcentrationAnesthesiaSurgical ProcedureCommon Carotid ArteryExternal Carotid ArteryInternal Carotid ArteryVessel Clips

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Leda, A. R., Dygert, L., Bertrand, L., Toborek, M. Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery. J. Vis. Exp. (119), e54804, doi:10.3791/54804 (2017).

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