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Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery
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Neuroscienze
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JoVE Journal Neuroscienze
Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery

Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery

DOI:
10.3791/54804-v

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06:41 min

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January 31, 2017

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, , ,
1Department of Biochemistry and Molecular Biology, Miller School of Medicine,University of Miami, 2The Jerzy Kukuczka Academy of Physical Education

Capitoli

  • 00:05Titolo
  • 00:39Dissection of the Common Carotid Artery
  • 02:31Preparation of the CCA for Substance Infusion
  • 03:38Substance Infusion via the ICA
  • 04:31Post Infusion Procedures
  • 05:22Results: Delivery of HIV and GFP-tagged CD63
  • 06:09Conclusion

Summary

Traduzione automatica

Traduzione automatica

The present protocol describes a mouse microsurgery infusion technique, which effectively delivers substances directly into the brain via the internal carotid artery.

Tags

Mouse MicrosurgeryInfusion TechniqueTargeted Substance DeliveryCNSInternal Carotid ArteryNeuroscienzeDrug DeliveryPathogenExosomeMinimal TraumaNeuronal NetworkBrain ConcentrationAnesthesiaSurgical ProcedureCommon Carotid ArteryExternal Carotid ArteryInternal Carotid ArteryVessel Clips

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