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Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery
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Neuroscienze
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JoVE Journal Neuroscienze
Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery

Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery

10,629 Views

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06:41 min

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January 31, 2017

DOI:

10.3791/54804-v

DOI:
10.3791/54804-v

•

06:41 min
January 31, 2017

•

8 Views
, , ,
1Department of Biochemistry and Molecular Biology, Miller School of Medicine,University of Miami, 2The Jerzy Kukuczka Academy of Physical Education

Summary

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The present protocol describes a mouse microsurgery infusion technique, which effectively delivers substances directly into the brain via the internal carotid artery.

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Mouse MicrosurgeryInfusion TechniqueTargeted Substance DeliveryCNSInternal Carotid ArteryNeuroscienzeDrug DeliveryPathogenExosomeMinimal TraumaNeuronal NetworkBrain ConcentrationAnesthesiaSurgical ProcedureCommon Carotid ArteryExternal Carotid ArteryInternal Carotid ArteryVessel Clips

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Cite this Article

Leda, A. R., Dygert, L., Bertrand, L., Toborek, M. Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery. J. Vis. Exp. (119), e54804, doi:10.3791/54804 (2017).

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