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Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery
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神经科学
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JoVE 杂志 神经科学
Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery

Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery

10,629 Views

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06:41 min

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January 31, 2017

DOI:

10.3791/54804-v

DOI:
10.3791/54804-v

•

06:41 min
January 31, 2017

•

8 Views
, , ,
1Department of Biochemistry and Molecular Biology, Miller School of Medicine,University of Miami, 2The Jerzy Kukuczka Academy of Physical Education

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The present protocol describes a mouse microsurgery infusion technique, which effectively delivers substances directly into the brain via the internal carotid artery.

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Mouse MicrosurgeryInfusion TechniqueTargeted Substance DeliveryCNSInternal Carotid Artery神经科学Drug DeliveryPathogenExosomeMinimal TraumaNeuronal NetworkBrain ConcentrationAnesthesiaSurgical ProcedureCommon Carotid ArteryExternal Carotid ArteryInternal Carotid ArteryVessel Clips

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Leda, A. R., Dygert, L., Bertrand, L., Toborek, M. Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery. J. Vis. Exp. (119), e54804, doi:10.3791/54804 (2017).

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