JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
In Vivo Two-photon Imaging Of Experience-dependent Molecular Changes In Cortical Neurons
21,313 Views
•
10:07 min
•
January 05, 2013
DOI:
1Unit on Neural Circuits and Adaptive Behaviors, Genes Cognition and Psychosis Program,National Institute of Mental Health, 2Department of Neuroscience,Brown University – National Institutes of Health Graduate Partnership Program, 3Section on Synaptic Pharmacology, Laboratory for Integrative Neuroscience,National Institute on Alcohol Abuse and Alcoholism, 4Champalimaud Neuroscience Programme,Champalimaud Center for the Unknown
Summary
Automatically generated
Experience-dependent molecular changes in neurons are essential for the brain's ability to adapt in response to behavioral challenges. An in vivo two-photon imaging method is described here that allows the tracking of such molecular changes in individual cortical neurons through genetically encoded reporters.
Read Article
Cite this Article
Cao, V. Y., Ye, Y., Mastwal, S. S., Lovinger, D. M., Costa, R. M., Wang, K. H. In Vivo Two-photon Imaging Of Experience-dependent Molecular Changes In Cortical Neurons. J. Vis. Exp. (71), e50148, doi:10.3791/50148 (2013).
Copy