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BS3化学架橋アッセイ:げっ歯類の脳における細胞表面GABAA 受容体提示に対する慢性ストレスの影響の評価
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Journal JoVE Neurosciences
BS3 Chemical Crosslinking Assay: Evaluating the Effect of Chronic Stress on Cell Surface GABAA Receptor Presentation in the Rodent Brain
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BS3化学架橋アッセイ:げっ歯類の脳における細胞表面GABAA 受容体提示に対する慢性ストレスの影響の評価

836 Views

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05:17 min

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May 26, 2023

DOI:

10.3791/65063-v

DOI:
10.3791/65063-v

•

05:17 min
May 26, 2023

•

5 Views
, , , ,
1Centre for Addiction and Mental Health (CAMH),Campbell Family Mental Health Research Institute, 2Department of Pharmacology and Toxicology,University of Toronto, 3Department of Psychiatry,University of Toronto

Summary

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BS3化学架橋アッセイは、慢性心理社会的ストレス条件下でのマウス脳における細胞表面GABAA 受容体発現の減少を明らかにします。

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Sumitomo, A., Zhou, R., Prevot, T., Sibille, E., Tomoda, T. BS3 Chemical Crosslinking Assay: Evaluating the Effect of Chronic Stress on Cell Surface GABAA Receptor Presentation in the Rodent Brain. J. Vis. Exp. (195), e65063, doi:10.3791/65063 (2023).

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