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BS3 化学交联测定：评估慢性应激对啮齿动物大脑中细胞表面 GABA_A 受体呈递的影响

JoVE Revista
Neurociencias

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JoVE Revista Neurociencias

BS3 Chemical Crosslinking Assay: Evaluating the Effect of Chronic Stress on Cell Surface GABA_A Receptor Presentation in the Rodent Brain

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BS3 化学交联测定：评估慢性应激对啮齿动物大脑中细胞表面 GABA_A 受体呈递的影响

861 Views

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05:17 min

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May 26, 2023

DOI:

10.3791/65063-v

DOI:

10.3791/65063-v

•

05:17 min

May 26, 2023

•

5 Views

Akiko Sumitomo¹, Runhao Zhou^1,2, Thomas Prevot^1,3, Etienne Sibille^1,2,3, Toshifumi Tomoda^1,3

¹Centre for Addiction and Mental Health (CAMH),Campbell Family Mental Health Research Institute, ²Department of Pharmacology and Toxicology,University of Toronto, ³Department of Psychiatry,University of Toronto

Summary

BS3化学交联测定显示，在慢性社会心理应激条件下，小鼠大脑中细胞表面GABA_A 受体表达减少。

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