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小鼠中人类胸膜皮质瘤的PET/CT的植入与监测
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Inmunología y contagio
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JoVE Revista Inmunología y contagio
Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
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小鼠中人类胸膜皮质瘤的PET/CT的植入与监测

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07:54 min

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December 21, 2019

DOI:

10.3791/60272-v

DOI:
10.3791/60272-v

•

07:54 min
December 21, 2019

•

1 Views
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1MicroPET/SPECT/CT Imaging Laboratory, Centre for BioMedical Imaging (CIBM), Division of Nuclear Medicine and Molecular Imaging,University Hospitals and University of Geneva, 2Division of Thoracic and Endocrine Surgery,University Hospitals and University of Geneva

Summary

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本文介绍了通过将H2052/484中皮瘤细胞植入免疫功能性贫血小鼠胸腔，生成人类胸膜中皮瘤的正交小鼠模型。通过非侵入性多式联运 =18F_-2-fluo-2-脱氧-D-葡萄糖正电子发射断层扫描和计算机断层成像，对胸腔内肿瘤的发展进行了纵向监测。

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Orthotopic ModelPleural MesotheliomaAthymic MicePET/CTImplantationMonitoringAnesthesiaBuprenorphinePovidone-iodineCell SuspensionHamilton SyringeAbsorbable SuturesFDGDose CalculatorRadioactivity

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Cite this Article

Colin, D. J., Bejuy, O., Germain, S., Triponez, F., Serre-Beinier, V. Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice. J. Vis. Exp. (154), e60272, doi:10.3791/60272 (2019).

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