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Bioluminescence Imaging of NADPH Oxidase Activity in Different Animal Models
JoVE Journal
Immunologie und Infektion
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JoVE Journal Immunologie und Infektion
Bioluminescence Imaging of NADPH Oxidase Activity in Different Animal Models

Bioluminescence Imaging of NADPH Oxidase Activity in Different Animal Models

16,072 Views

10:42 min

October 22, 2012

DOI:

10:42 min
October 22, 2012

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Summary

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NADPH oxidase is the major source of reactive oxygen species (ROS) in phagocytes. Because of the ephemeral nature of ROS, it is difficult to measure and monitor ROS levels in living animals. A minimally invasive method for serial quantification of ROS in living mice is described.

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